cancer

Pere Pubill i Calaf, better known as Peret, died at noon on Wednesday in a Barcelonan hospital, aged 79. The singer, guitar player and composer Peret was considered to be the 'father' of the so-called Catalan rumba, a fusion music style mixing Afro-Cuban mambo with flamenco and rock and roll. This rhythm was born in the 1950s within Barcelona's Gipsy community and became increasingly popular in the 1960s thanks to some of Peret's hits. Soon it became part of Catalonia's culture and common heritage, being extremely popular and receiving institutional recognition. Peret started his musical career extremely young in the 1940s. He published a total of 27 albums, and he was about to release his first disc entirely in Catalan. In his last years, he became particularly active in social and political movements, criticising poverty and supporting Catalan self-determination. A few weeks ago, he issued a press release announcing he was undergoing anti-cancer treatment.

A team of surgeons at the Sant Joan de Déu Hospital in the Catalan capital successfully removed a tumour from a five year old child by first preparing and practicing the “highly complex” procedure on a 3D printed tumour. The child had neuroblastoma, a difficult cancer to extirpate because of the surrounding blood vessels and arteries. In such cases, testing the procedure in advance "is key" because it allows surgeons to study the most effective way of extracting the tumour without damaging other tissues, and to test the method before surgery. This has been possible thanks to the use of a 3D replica of the tumour.

Researchers from the University of Barcelona (UB) and the Catalan capital’s CELLEX Biomedical Research Centre (IDIBAPS-UB) have found the essential role played by cholesterol in cell mobility and tissue invasion, which also means its role in cancer propagation. In fact, this research, led by Professor Carles Enrich, is a key study for better understanding of cancer metastasis – the process in which cancer cells invade healthy tissues – and progresses the discussion on the relationship between cholesterol levels and cancer incidence. The paper is published in open access ‘Cell Reports’. In short they found that the so-called “bad” cholesterol (LDL cells) promotes cell mobility while “good” cholesterol (HDL cells) avoids cell propagation. The study opens new therapeutic paths to blocking cancer metastasis.

A surgical team of the Hospital de Bellvitge in L’Hospitalet de Llobregat, Greater Barcelona, has successfully reconstructed the breasts of 22 women suffering from cancer in one single surgery. This world pioneer medical procedure, consisting in transplanting dorsal muscle on to the removed breast, allows patients to “turn the page” on the disease much more quickly, according to Joan Maria Vinyals, the Head of plastic surgery. Indeed, this “complete and radical reconstruction”, which includes the nipple and areola, avoids having to proceed to a second surgery and erases the usual trauma regarding aesthetic concerns. Leonor Garrido, one of the patients, stated that the technique “had improved a lot” her quality of life since she had her tumour removed and the breast entirely reconstructed immediatly after.

The Catalan Institute of Oncology (ICO) and Roche pharmaceutical company have signed an agreement stating that the Catalan public institute will pay for treatments against cancer depending on clinical results adapted to each specific patient. For now, the agreement provides that Roche will supply two drugs against the most common cancers, mostly breast and colon. According to the agreement, the probabilities of success will be thoroughly examined and if they meet the requirements, the Catalan Government will fully pay for the treatment. If not, Roche will assume the costs progressively according to the degree of success.

Doctor Joan Massagué has been appointed Scientific Director of the Sloan-Kettering Institute in New York , the world’s leading cancer research centre, which is part of the Memorial Sloan-Kettering Cancer Centre. The Catalan scientist has been chosen by an international expert committee and will take office on the 1^st of January 2014. The President and CEO of the Memorial Sloan-Kettering, Craig B. Thomson, said that Massagué had been given the job for his “exemplarity as a scientist” and because he is an “international leader” in the study of metastasis and factors regulating cell growth. This announcement follows last year’s appointment of another Catalan Doctor, Josep Baselga, as the Physician-in-Chief of the Memorial Sloan-Kettering Cancer Centre. Both Baselga and Massagué will continue to combine their responsibilities in New York with their research in Barcelona.

The President of FC Barcelona, Sandro Rosell, announced on Friday evening that the Catalan manager will not continue at Barça due to ongoing treatment of his illness. FC Barcelona will not travel to Poland on Saturday. During this evening’s press conference, president Rosell announced: “After evaluating the results from the routine check-ups, which Tito Vilanova underwent this week, he was presented with the option to continue treatment to control his illness which will make it impossible to continue his responsibilities as the first team manager of the senior side.” On 22 November of 2011 FC Barcelona announced that Tito Vilanova had a tumor on his parotid gland and he underwent emergency surgery.

The French defender has signed a season long deal, with the option of a further year. Abidal returns to the football club where he played from 2000-2002 before signing for Lyon. Abidal played for Barça between 2007 and 2013. The Catalan club and the player announced in late May he will not continue playing with FC Barcelona in the next season. Abidal’s touching farewell took place in early June at the Camp Nou, after he had played the last 15 minutes of the FC Barcelona vs Malaga game.

50% of tumours are related to mutations of this gene, according to the researchers. A study developed by the Bellvitge Institute of Biomedical Research (IBIDELL), based in Greater Barcelona, and the University of Cincinnati have discovered the role of the noncoding 5S rRNA molecule. This molecule regulates the P53 Tumour Suppressor Gene, which protects healthy cells from turning into cancerous cells. When the cell functions correctly, the levels of P53 are low and stable, but when something wrong is detected, the levels increase and cause the cell’s death, avoiding the development of a tumour. The director of the study, George Thomas, explained that understanding how the P53 works and regulates itself is extremely important since “more than half of the tumours present mutations of this gene”.

FC Barcelona’s Coach has landed on Tuesday morning, at about 8:05 at Barcelona El Prat Airport, after two months in New York when dealing with his illness. Jordi Roura and Aureli Altimira, who joined him on the flight home, will be taking this afternoon’s training session at the Ciutat Esportiva. Last December Vilanova underwent surgery for his parotid ailment relapse and in January he flew to the States to continue with his cancer treatment. In late 2011, Tito Vilanova had a first tumour removed from his parotid gland.

The Catalan Institute of Oncology (ICO) has introduced a world pioneering technique which allows four out of five patients who cannot undergo surgery to survive the illness. This technique causes less after-effects than the traditional radiotherapy. Furthermore, statistics show that with the regular treatment, two thirds of these patients die. However, Ferran Gadea, the Head of the Radiotherapy and Oncology Service, says that the best option to cure a lung cancer is still to undergo the operation when possible.

This is a real stride for the cancer research. The effects of a protein called condensing on colorectal cancer have been found out by a team of Molecular Biology and Biochemistry experts, at the Research Centre for Nanomedicine (CIBBIN-Nanomedicine) at the Vall d'Hebon Research Institute. The researchers have discovered that condensin helps the tumor cells to divide rapidly, so its inhibition leads to the death of tumour cells. The results of this research were published in the 'Journal of Biology and Chemistry', and they constitute a real hope for the fight against colorectal cancer.

Researchers from the Catalan Institute of Oncology have led the largest international study on breast cance4r and nutrition. The 8-year study has been based on 335,062 women between 35 and 70 years old. It has involved 23 centres in 10 European countries and it has been published in the ‘International Journal of Cancer’. The study concludes that the Mediterranean diet can reduce the risk of breast cancer by 6% among women in general and 7% in the case of post-menopausal patients.

A research group led by Catalan doctor Joaquim Bellmunt at the Hospital del Mar has shown in a study how important the time between two chemotherapy treatments is in increasing the curing rates of bladder cancer. The study was published by the journal ‘European Urology’ and has encouraged the researchers to develop new drugs for treating this type of tumour.

The series, produced by the Catalan Public Television Broadcaster and Filmax, has been exported to several countries and Steven Spielberg and Marta Kauffman are going to shoot a remake for the ABC network. ‘Polseres vermelles’ – which literally means ‘red bracelets’ in Catalan - describes the life of a group of six teenagers who live in a hospital as patients. It is based on the personal experiences of its creator, Albert Espinosa, who had cancer as a child. The first season was aired in 2011 and it became a huge success with audiences. The second season premiered on Thursday and will be broadcast as from Monday on TV3 at prime time.